Clinical trials have suggested that curcumin may have a more marked anti-inflammatory effect than hydrocortisone, and it is believed to be more antioxidant than vitamin E. It is of value in the treatment of rheumatic and arthritic conditions. Turmeric has a bitter action that stimulates the appetite and digestive secretions. It also increases mucus production, protecting the lining of the stomach. Its cholesterol-lowering action means that it is a valuable remedy for reducing the risk of heart attack or stroke. Turmeric is contraindicated in biliary obstruction.